Libido & hormones
Libido & Hormones: PT-141, Kisspeptin and Hormonal Axes
Hormonal axes and sexual function: clinical data with the context attached.
7 matching articles
Compound

5 September 2026 · 12 min read
Growth Hormone Secretagogues: One Approved Drug, Several Research Compounds, and the Difference
Tesamorelin is an FDA-approved medicine with phase 3 trial data. Ipamorelin and sermorelin are not approved for general use and rest on far thinner evidence. What separates a licensed GHRH analogue from an online 'GH peptide'.
Ipamorelin · Tesamorelin · Sermorelin · Growth hormone

31 August 2026 · 5 min read
Evaluating Mod GRF 1-29 (CJC-1295 Without DAC): Secretagogue Kinetics, Receptor Dynamics, and Experimental Limitations
An editorial review examining the short-acting GHRH analog Mod GRF 1-29 (CJC-1295 no DAC), its physiological mechanism, pulsatile release profiles, and comparative distinction from long-acting formulations.
Ipamorelin · CJC-1295 · Sermorelin · Growth hormone

31 August 2026 · 14 min read
What Is Retatrutide? Mechanism, Phase 3 Results and Approval Status
Retatrutide (LY3437943) is an investigational triple hormone receptor agonist at the GIP, GLP-1 and glucagon receptors. What the peer-reviewed trials show, how the 2026 topline Phase 3 results should be read, and why it is approved nowhere.
Semaglutide · Tirzepatide · Retatrutide

31 August 2026 · 6 min read
Selectivity in Growth Hormone Secretagogues: A Desk Review of Ipamorelin
An editorial examination of ipamorelin’s receptor selectivity, its historical development, and the current state of preclinical research regarding growth hormone axis modulation.
Ipamorelin · Hexarelin · Growth hormone

31 August 2026 · 4 min read
Evaluating Ipamorelin: Selectivity, Endocrine Dynamics, and Preclinical Evidence
An editorial analysis of ipamorelin, examining its ghrelin-receptor selectivity, pulsatile growth hormone secretagogue profile, preclinical data on bone and gut motility, and key analytical considerations for research environments.
Ipamorelin · Growth hormone

31 August 2026 · 5 min read
Mechanistic Precision and Metabolic Trade-Offs: A Desk Review of Tesamorelin
An analytical evaluation of Tesamorelin, examining its structural stability as a GHRH analogue, visceral adiposity trial data, glycemic impact, and neurodegenerative research frontiers.
Ipamorelin · Tesamorelin · Growth hormone

31 August 2026 · 5 min read
Evaluating Sermorelin: Mechanistic Insights and Evidence in Somatotropic Axis Modulation
An editorial examination of Sermorelin acetate, analyzing its mechanism of action, pituitary feedback dynamics, and clinical evidence comparing GHRH secretagogues to direct growth hormone replacement.
Sermorelin · Growth hormone